If you are receiving this email it almost certainly means that you have a personal interest in gastrointestinal health. You probably keep an eye on the headlines, or scroll through Amazon hoping to see some new product that holds promise.
I am no different than you, and when I stumbled across an ingredient that had won the "nutra ingredient of the year" in 2020, I immediately went looking for a product that featured it. Only I didn't find it. Not in the way I was hoping to at least. I couldn't believe that nobody had this as a standalone supplement! 8 months later here we are... and now I'm excited to announce the arrival of our PREbiotic GOLD.
Almost everyone knows about PRObiotics at this point. (Speaking of which, did you hear that the new and improved PRO-B11 is back? More on that later...) But not everybody knows about PREbiotics.
Prebiotics are nondigestible fermentable fibers that feed the bacteria in your gastrointestinal system. If you have heard of them, then you are probably familiar with FOS, GOS, and Inulin. These are the most common types in supplement form. They have very simple molecular structures and are rapidly fermented by the first bacteria to encounter them. This rapid fermentation leads to a few things that nobody wants, namely GAS and BLOATING. There's something else going on in there that does not reveal iself in such an obvious manner, but is in fact a way bigger problem.
Simple prebiotics like FOS/GOS/Inulin may only benefit the handful of bacterial species that are the fastest to ferment. This can cause an overgrowth of these few species to the detriment of the overall diversity of the gut microbiome.
Humans cannot digest large portions of the foods that we eat. People with digestive disorders even less so. We rely on bacterial enzymes to help us extract nutrients from the parts of our food that we cannot digest on our own. Different types of bacteria have different types of enzymes, and their byproducts have different functions within our bodies. We NEED a broad spectrum of these bacteria for maximum nutrient absoroption, but also for the other benefits they provide.
We're staying on the topic of PREbiotics, but let's take a quick detour over to POSTbiotics...
POSTbiotics are "functional bioactive compounds generated by gut bacteria during fermentation which promote gastrointestinal health." Short Chain Fatty Acids (SCFAs), primarily acetate, propionate, and butyrate are the end products of the bacterial fermentation that we've been talking about. Postbiotics have immunomodulating and antimicrobial effects, and most importantly for us, anti-inflammatory effects.
The other two are important, but let's shine a spotlight on butyrate! Butyrate promotes the repair and regeneration of the cells that line your intestinal tract, called epithelial cells. Butyrate provides an average of 70% of the energy that your colon and the colonocytes (epithelial cells in the colon) need.
Now here's where we circle back around to why the fast fermentation of FOS/GOS/Inulin is less than ideal.
Colonocytes use butyrate instead of sugars to generate energy for growth. If there is no butyrate, the colonocytes will eat their own proteins to survive. This causes breaks in the mucosal layer, leading to ulcers, and loosend the tight junctions of your gut lining.
Okay, enough already, get to the point!!!
We're getting there I promise!
This is where we introduce the all-new Intestinal Fortitude PREbiotic GOLD!
DAH DAH NAH NAH
PREbiotic GOLD is a high-quality, freeze-dried powder derived from non-GMO New Zealand Gold Kiwifruit. And while every capsule packs the wholefood goodness of 2 Gold Kiwifruit, it's the PECTIN that we are excited about here.
PREbiotic GOLD is gently processed and retains the kiwifruit pectin's complex structure in its natural form. The molecular structure has a "branch" on either end of the "core structure". I like to look at it like an OREO cookie. You've got the cookie on either end and that wonderful creme in the middle.
More complex fiber like kiwifruit pectin requires a variety of bacterial species with different degradative enzymes to break down and ferment "branches". Chains of different bacteria may develop, with additional organisms living off the waste products the primary fermenters. As the pectin passes through the colon and is fermented, new sections open and additional bacteria are able to come in and feed on it. The slower rate of fermentation equals a bigger variety of bacterial species that are able to feed and grow, and this will increase the diversity of your microbiome.
Does everybody remember what POSTbiotics are? Well, when PREbiotics are rapidly fermented early in the colon you enf up with most of the beneficial byproducts (such as SCFAs) accumulating in one section. However SCFAs, especially butyrate, are desperately needed in places other than just the start of the colon.
When the fermentation process is slow and you get a large community of species participating, the SCFAs will the be deposited along the entire length of the colon. Because you have that diverse community "hanging on" to the pectin as it passes, many of them will "let go" along the way. This will increase the diversity of the microbiome throughout the gut, rather than just in one place.
Now I know what you are thinking... what about that fantasic creme center?!?!? Who gets to eat that?
Well, I'm glad you asked, because this the "piece de resistance"! PREbiotic GOLD is called a precision prebiotic because it ultimately has a precise target in mind. The lucky recipient of the pectin "core" or the creme in this example, is a little guy call Faecalibacterium prausnitzii. Or F. prau as his homies call him.
F. prau is one of the most abundant bacterial species in the human gut, accounting for around 5% othe the total bacterial population of a healthy individual. F. prau dramatically increases the amount of butyrate inside the gut. And remember the benefits of butyrate are...
- Energy source for colonocytes
- Mucus synthesis
- Ion absorption
- Improved intestinal cell life cycle
- Enhanced intestinal barrier function
- Promotes cell death in malignant (bad) cells
- Helps control pathogens
- Controls intestinal motility
Unfortunately, a lack of F. prau is associated with IBD, IBS, and other gastrointestinal issues. So, let's just get some more right?!?!? It's not that simple.
When we were researching bacterial species for our PRO-B11 prbiotic supplement we came across the name faecalibacaterium prausnitzii over and over again in the scientific literature. When we first spoke with our manufacturing partner we told them that it was the the top of our list for strains we wanted to include. that's when we found our that F. prau is not available as a commercial probiotic supplement because it dies almost instantly when it comes into contact with oxygen.
Since we can't get it from an external source, the best strategy is to do all that you can to help the F. prau that you already have. Research shows that Gold kiwifruit pectin helps F. prau communites to flourish and recover. One clinical study showed that F. prau levels doubled in patients that supplemented with it. While taking the F. prau itself is not an easy option, taking the precision prebiotic it needs to thrive is!!!
One PREbiotic GOLD capsule daily is all you need to start fertilizing the garden that is your microbiome.
Oh, we almost forgot! While your FEEDING your garden, why not SEED your garden with the new and improved PRO-B11 probiotic supplement?!?!?
After a little vacation, your favorite probiotic is back and better than ever. The same exact blend of bacterial species that you know and love, but double the CFU count.
PRO-B11 was developed in collaboration with one of the World's leading probiotic manufacturers. It only features bacterial strains that have been proven to be effective in treating Inflammatory Bowel Disease, and it includes them in proportions that mirror those of a healthy gastrointestinal system.
We personally pined for them, and plenty of you let us know how much you have been missing them. So we brought them back!!!
If you are still reading... thank you! I know it was a lot, but hopefully you found it informative. If all that made sense to you and you are interested in trying what is potentially the best PREbiotic available, then head back to the email and take advantage of the offer!